#31 – 3 Fundamental Root Causes of Insulin Resistance

This episode takes a fresh look at the 3 fundamental molecular root causes of insulin resistance using some familiar storylines from prior episodes combined with some new story hooks to help you understand the science of insulin resistance. We cover the following: Quick review of insulin…


#26 – The Science of GLP-1 Drugs and Natural Weight Loss

GLP-1 drugs have been all over the headlines and the global demand for using these drugs for weight loss has been significant. GLP-1 belongs to a family of gut-based hormones called incretins. In this episode I'll teach you about the fascinating incretin system and how you can influence it…


Is Erythritol a Safe Sweetener?

Background The recent headlines about erythritol and its possible association with cardiovascular disease has led to a heavy stream of questions flooding my inbox. As always, there's so much more to this story than the headlines suggest. I'd like to use this study as another opportunity to…


#20 – Glucose Variability: An Essential Metabolic Metric

Glucose variability (GV) is an important metric that expands upon the current limited application of fasting blood glucose and hemoglobin A1C. In this episode we'll discuss: The limitations of A1C and fasting blood glucose What is GV and why it matters? How GV is related to inflammation and…


#19 – Rethinking Hemoglobin A1C and Are You Truly Prediabetic?

The hemoglobin A1C is a useful, yet imperfect glycemic marker which we'll explore further in this episode where we discuss: The origins of the glycohemoglobin test (aka A1C) The flaws of A1C testing and why you may not be prediabetic Insulin resistant markers that should accompany A1C testing…


#18 – Multiethnic Metabolism and Heart Disease Risk

There are significant ethnicity-specific differences in metabolism and heart disease risk that are not often discussed. In this episode we cover: A brief overview of insulin resistance (IR) and the renin angiotensin system (aka RAS) How IR and RAS present in major ethnic groups like African…


#17 – Blood Pressure, Body Fat, and Sodium

I'm going to explain the interaction between blood pressure, body fat, and sodium by explaining the all important RAAS (renin-angiotensin-aldosterone system). Understanding this system can help you optimize blood pressure, heart, and overall vascular health. We'll discuss the following:…


#2 – Deep Dive Into Glut Subtypes and Exercise

Glucose transporters (aka Glut) are a key protein that shuttles glucose into cells.  Understanding Glut helps you understand how your body transports and utilizes sugar, and how you can impact your glucose metabolism through lifestyle changes like exercise.  We'll use some clever mnemonics to…


#1 – Using Mangos to Explain Insulin and Glut4

This is the first of a series of episodes that digs deep into insulin's actions and uses what I call the "mango cell model" so you understand the key components of cell structure.  I'm also going to introduce a key glucose transporter called GLUT and end with my opinion about mangos and fruits…


#3 – Beta Cell Batteries, Fasting, and Ketosis

Beta cells are the insulin-producing cells in our pancreas and their durability is a key factor in promoting longevity and optimal health.  In this episode I use the battery analogy to explain how beta cells work and what actions you can take to preserve your beta cell battery life which helps…


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