#30 – Protein, Fasting, Ketosis, and Insulin Resistance
This episode digs deep into protein and more specifically amino acids (protein building blocks) and their role in metabolism, weight control, insulin resistance, and overall health. We cover some of the following: Quick overview of mitochondrial metabolism Introducing protein and amino acids…
August 10, 2023
#29 – Acetyl CoA, Citrate, and the Metabolic Merry-Go-Round
I've selected 2 key metabolic ingredients, Acetyl CoA and Citrate, to explain nutrition metabolism in further detail. I've also selected a different storyline, the mitochondrial amusement park and the Kreb's merry-go-round, to help you visualize some of the most fundamental steps of metabolism.…
July 6, 2023
#28 – Mental and Metabolic Effects of Work from Home
The mental and metabolic impact of human beings predominantly or exclusively working from home has been profound. I've noticed significant increases in insulin resistant conditions including premature heart disease and a deterioration in mental health. All of these risks existed pre-pandemic,…
June 21, 2023
#27 – Targeting Visceral and Subcutaneous Fat Loss
I see lots of patients in my clinic who aim to lose body fat and have become well versed in the different types of body fat, specifically subcutaneous adipose tissue (aka SAT) and visceral adipose tissue (aka VAT). Although VAT and SAT are both fat, they represent different health risks and there…
May 3, 2023
#26 – The Science of GLP-1 Drugs and Natural Weight Loss
GLP-1 drugs have been all over the headlines and the global demand for using these drugs for weight loss has been significant. GLP-1 belongs to a family of gut-based hormones called incretins. In this episode I'll teach you about the fascinating incretin system and how you can influence it…
March 28, 2023
#25 – The Critical Pentose Phosphate Pathway and Erythritol
The pentose phosphate pathway, which I refer to as P3, is one of my favorite metabolic pathways and one that gets far less attention than glycolysis, gluconeogenesis, and Krebs, yet plays such a key role in our body. In this episode we go over the following: Brief refresher on glycolysis and…
March 14, 2023
#24 – Metabyte #1: Insulin Lock and Key
In this Metabyte (shorter episode), I review the interaction of the insulin hormone and its receptor on the surface of the muscle cells using a slice of chocolate cake, a lock and key, and a reference to Indiana Jones. Check out this episode!
January 24, 2023
#23 – Holistic Hypocrisy and Supplement Scams
Call it holistic, functional, metabolic, integrative, longevity, or whatever, but this episode expresses some of my concerns about the direction of what I refer to as the rising "alt health" movement. Interestingly, I'm part of both alt health and mainstream medicine, so I'll share my take from…
September 7, 2022
#22 – Lipids Part 2: Cholesterol Numbers and Heart Disease Risk
In this episode we will tie together cholesterol metabolism using the boat vehicular model from Part 1, and understanding your own cholesterol results in greater depth. My free cholesterol e-book here summarizes key numbers and concepts discussed in this episode. We'll discuss the following:…
June 21, 2022
# 21 – Lipids Part 1: Metabolic Trafficking using Cars and Boats
Lipid (cholesterol) physiology is complicated, but essential for you to understand as part of metabolism, health, and longevity. Let's simplify lipids (and glucose) using cars, boats, and traffic. This sets the foundation for future episodes where I discuss the practical implications of lipids…
May 24, 2022